In an period the place sustainability and traceability are high of thoughts for shoppers, the sourcing story of Mangixyl™ highlights our dedication to our Firm Goal. The mango leaves are collected in collaboration with the Affiliation Bendia, primarily based in Koro village (Burkina Faso, Africa). The affiliation is a women-led initiative to contribute to the advance of the dwelling circumstances of the neighborhood. Derived from the inexperienced fractionation of mango leaves, Mangixyl™ is a beauty innovation capable of activate particular receptors of gene’s pathway usually regulated by the extremely potent retinoic acid.
Mangixyl™, the moral method to sort out oily pores and skin points
To struggle towards the seen look of oily pores and skin, making use of mattifying powders with the intention to take up sebum is an answer; but it surely requires many functions throughout the day, and the quantity of product to use is commonly seen on the face. If generally the sebum might be perceived as an enemy for the pores and skin look, it’s vital to understand that its steadiness is important. Certainly, the sebum is a vital a part of pores and skin well being, because it participates to the hydration of the dermis and contributes to the suppleness and softness of the dermis.
By crafting Mangixyl™, Givaudan Energetic Magnificence goals to alleviate shoppers from the discomfort brought on by oily pores and skin. The ingredient prompts some receptors of the retinoic acid-regulated genes pathway and reduces the synthesis of lipids on all pores and skin ethnicities.
Sebum discount for all complexions
Reflecting the corporate dedication to inclusive magnificence, Mangixyl™ is a genderless, common ingredient that’s appropriate for all age teams and pores and skin tones. To guage the advantages of the ingredient, three medical checks had been performed in double blind versus placebo, on volunteers from completely different pores and skin complexions: African (South Africa), Asian (China) and Caucasian (Europe). The measurement of sebum amount was carried out on cheeks and nostril space at D0 and D28 by sebumeter or sebufix. The examined product was a cream, utilized twice a day on the face, containing 1% Mangixyl™ for Caucasian volunteers and a pair of% of lively for Asian and African volunteers. It seems that Mangixyl™ considerably reduces, globally twice higher than placebo, the amount of sebum in solely in a month for all pores and skin complexions.
This totally pure and microbiome-friendly lively ingredient regulates sebum manufacturing (down to fifteen.9% after one month relying on complexion) to alleviate the discomfort brought on by oily pores and skin – a widespread concern for shoppers all over the world. Double-blind checks versus placebo research have additionally proven a 49.5% enchancment in sebum high quality.
A microbiome-friendly lively ingredient
Inclined-to-acne pores and skin is a multifactorial situation, resulting in pimples and irritation, and involving an extra of sebum manufacturing. Because of this Mangixyl™ was additionally examined on a number of elements associated to zits. Throughout in vitro take a look at, Mangixyl™ confirmed a 29% inhibitory motion on C. acnes lipase exercise.
Within the double blind versus placebo medical research carried out on European girls with oily pores and skin, a big discount by x2.4 of porphyrins depth is noticed (versus placebo) for 80% of volunteers, reflecting the change of C.acnes metabolism on the pores and skin of volunteers, after one month with Mangixyl™ at 1%. Relative abundance evolution of various bacterial genera confirmed that Mangixyl™ at 1% protected the pores and skin microbiota over time, whereas the placebo group confirmed a pores and skin dysbiosis.
Creating for tomorrow
Mangixyl™ is the proper all-round ingredient for creating skincare options that not solely free shoppers from oily pores and skin, but in addition meet the rising demand for sustainable, traceable and inclusive merchandise.
Do you know? 
71% of shoppers say that oily pores and skin in a supply of discomfort
63% say that treating oily pores and skin is tough
89% could be considering a pure product that helps steadiness sebum manufacturing
To encourage the wonder trade, Mangixyl™ was featured in a brand new advertising and marketing idea known as S3D® Womango. Because of its three ranges of motion, this light-weight, mattifying day cream instantly reduces shine, balances sebum manufacturing all day lengthy and reduces extra sebum over time – providing shoppers a serving to hand of their journey in direction of a clearer complexion.